Interpretes Habituales

- Ellen Pompeo
- Patrick Dempsey
- Sandra Oh
- Katherine Heigl
- Justin Chambers
- T.R.Knight
- Isaiah Washington
- Chandra Wilson
- James Pickens Jr
- Kate Walsh
- Sara Ramirez
- Eric Dane

Otros Interpretes que aparecen en la serie

- Martin Ighani
- Billy Wood
- Josh Bywater
- Brad Pennington
- Kathleen M. Darcy
- Grinnell Morris
- Richard Gilbert-Hill
- Sendhil Ramamurthy
- Sean Palmer
- Lynn Marie Stewart
- Kate Burton
- Moe Irvin
- Gregory Erff
- Robbie Troy
- Randall Arney

Directores

- Peter Horton
- Tony Goldwyn
- Adam Davidson
- John David Coles
- Scott Brazil
- Darnell Martin
- Sarah Pia Anderson
- Wendy Stantzler
- Wendey Stanzler
- Rob Corn
- David Paymer
- Wendy Stanzler
- Mark Tinkler
- Jeff Melman
- Lesli Linka Glatter